The Diggle Lab
Antibiotic resistance, bacteriocins, biofilms, quorum sensing, social interactions
Antibiotic resistance, bacteriocins, biofilms, quorum sensing, social interactions
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Bacteria communicate, cooperate and compete, resulting in a wide range of group behaviors such as dispersal, foraging, biofilm formation, chemical warfare and quorum sensing. Our group, based in the Center for Microbial Dynamics & Infection at Georgia Tech, studies microbial interactions and social behaviors and the implications for virulence and antimicrobial resistance.
Latest papers
Humphreys, J. R., Debebe, J., Diggle, S. P. & Winzer, K. (2023) Clostridial strain degeneration is driven by the loss of Spo0A activity. Frontiers in Microbiology. O’Connor, K., Zhao, C. Y., Mei, M. & Diggle, S. P. (2022) Frequency of quorum sensing mutations in Pseudomonas aeruginosa strains isolated from different environments. Microbiology. Azimi, S., Thomas, J., Cleland, S. E., Curtis, J. E., Goldberg, J. B. & Diggle, S. P. (2021) O-specific antigen-dependent surface hydrophobicity determines aggregate assembly type in Pseudomonas aeruginosa. mBio. Mei, M., Thomas, J. & Diggle, S. P. (2021) Heterogenous susceptibility to R-pyocins in populations of Pseudomonas aeruginosa sourced from cystic fibrosis lungs. mBio. Vanderwoude, J., Fleming, D., Azimi, S., Trivedi, U., Rumbaugh, K. P. & Diggle, S. P. (2020) The evolution of virulence in Pseudomonas aeruginosa during chronic wound infection. Proceedings of the Royal Society B. All publications |
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